Vaccinia Virus: From Crude Smallpox Vaccines to Elaborate Viral Vector Vaccine Design
Various vaccinia virus (VACV) strains were applied during the smallpox vaccination campaign to eradicate the variola virus worldwide.After the eradication Waterproof Breeks of smallpox, VACV gained popularity as a viral vector thanks to increasing innovations in genetic engineering and vaccine technology.Some VACV strains have been extensively used